Journal de pharmacocinétique et thérapeutique expérimentale

Abstrait

Why W neurons decreases and C neurons increases in fever?

K. M. Yacob

As you aware, if temperature increases (Absence of fever)after 31 degree Celsius , Warm sensitive neurons increase their firing rate and inhibit Cold sensitive neurons as core temperature increases. As temperature drops, the firing rate of Warm sensitive neurons decreases, reducing their inhibition, and Cold sensitive neurons which respond by increasing their firing rates.