Journal de pharmacologie cellulaire et moléculaire

Abstrait

The Configuration Robustness of a Functional Genome is Revealed by Single-Chromosome Fission Yeast Models

Jin-Qiu Zhou

The physical units that house genetic information are called chromosomes. Chromosome counts in eukarya differ amongst organisms; for example, the male ant Myrmecia pilosula has one chromosome, whereas the fern Ophioglossum reticulatum has hundreds Chromosome number reduction by fusion happened during the evolution of apes to humans, as evidenced by the strong resemblance between human chromosome 2 and two ancestral ape chromosomes 2A and 2B. It is unknown if changes in chromosomal counts over time in a particular species encourage speciation and offer adaptive advantages. Various chromosomes In an interphase nucleus, chromosomal territories (CTs) often occupy distinct areas.It is recognised that chromosomal architecture and spatial structure regulate gene expression and define cellular processes [1-15]. The tolerance for chromosome configuration changes, both organic and synthetic, varies. Thai Fea’s muntjacs (Muntiacus feae) exhibit 2n = 12, 13 (female), or 14 (female and male) .The karyotypes of the Indian muntjac (M. muntjak vaginalis) and Chinese muntjac (M. reevesi), two closely related species, are noticeably different.