Revue internationale de recherche et développement en pharmacie et sciences de la vie

Abstrait

OCULAR DRUG DELIVERY: ASSORTED OBSTRUCTIONS AND CONTEMPORARY PROGRESSES

Upendra Kumar Sharma, Amita Verma , Sunil Kuamr Prajapati and Himanshu Pandey

Carriage of medicaments assigned in the forms of conventional dosage is restricted to the eye; moreover, favorable drug concentrations in the destination tissues are not kept up for an extended time spread given that the eyes are escorted via an inimitable anatomy, physiology and biochemistry. The clearcut aim of designing a therapeutic system is to attain a desirable concentration of a drug at the active site for the relevant duration. A successful design of a drugdelivery system, therefore, desires an integrated knowledge of the drug molecule and the restrictions offered by the ocular route of administration. In last decade, with the emergence of miscellaneous powerful and multifaceted medicinal substitutes, the assortment of traditional ophthalmic preparations has progressively developed; drawing out considerably apart from ordinary solutions, suspensions and ointments, presently comprises a diversity of drug administration formats. Present communication echoes miscellaneous barriers and successive blossoms in the field of ocular therapeutics.