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Jung-Hee Lee and Chaisiri Chaichankul
At the present time, only few reports including systematic reviews of malignant peripheral nerve sheath tumors (MPNSTs) with spinal involvement have been existed. Although there were reports of both MPNSTs of paraspinal soft tissue (type 1) resulting in secondary vertebral destruction and MPNSTs primarily originated from intraosseous of vertebra itself (type 2), these kinds of tumors are exceptionally rare. In this present report, we hereby demonstrated a case of type 2 MPNSTs which is not related to neurofibromatosis type 1 (NF 1) occurring in the thoracic spine and reviewed the clinical, radiologic, and pathologic as well as shared part of our experience in treating this rare condition. Interestingly, MPNSTs usually have a high rate of recurrence both local and metastasis even in the cases of successful en bloc resection with adjuvant therapy, but not in ours for 5-year follow up.