Revue internationale de recherche et développement en pharmacie et sciences de la vie

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DIETRY FACTORS IN ALZHEIMER'S DISEASE: A COMPILATION OF HELPING EVIDENCES

Uma Mandla, Preety Sharma, Vivek Sharma

The increasing life expectancy of Indians is likely to result in an increase in age-related disorders like Alzheimer’s disease. Alzheimer’s disease is a chronic, progressive, untreatable neurodegenerative disorder characterized by apraxia, aphasia, agnosia and severe cognitive deficits. Several behavioural changes like anxiety, hallucinations, depression and delusions are also experienced. AD have a serious impact on families, caregivers, and the healthcare system in general. Although lot of theories and treatments have been proposed targeting pathophysiology of AD yet, current treatments are merely palliative and do little to slow the progression of the disease. Yet, a great deal of progress has been made in the understanding of AD and many promising therapies have entered clinical trials. Several of key areas have been recognized and out of them life style modifications and role of food stuff has been regarded as inseparable and crucial factor involved. Present review is an effort to investigate the status and role of different common food stuffs and supplements in pathogenesis of AD.