Pharmacologie clinique et biopharmaceutique

Abstrait

Application of New Biotechnologies for Prostate Cancer Treatment (Comparative Analysis of Brachytherapy, Cryosurgery, Laparoscopy, Robotic Arm and Cyberknife Methods)

Giuseppe Morgia, Chaled Alnakib and Giorgio Ivan Russo

Prostate cancer is the second most commonly diagnosed non-dermatologic malignancy among American men and the 6th most fatal cancer worldwide. Open field radical prostatectomy is the gold standard procedure for treatment of prostate cancer. Yet, several novel methodologies have been emerging lately, promising to be mini-invasive, to reduce complications related to surgery and to offer the patient a better quality of life thereafter. Among the latter, preservation of urinary and sexual function appear to be the most important. Some of such alternative treatments may be found applicable to patients with a life expectancy less than 10 years, or those unfit for surgery for other reasons. The present manuscript has been aimed to overview the most prominent novel methods for prostate cancer treatment, in attempt to point out the options and the rationale for choosing a method, or a combination of methods, for the best and the most effective treatment of prostate cancer.