Revue internationale de recherche et développement en pharmacie et sciences de la vie

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AN UPDATE ON HERB INDUCED CHRONIC KIDNEY DISEASES

Pranav vashisth, Dr.Vinay jain, Love singh chokotia, rajkumar sironiya, Harsha matoli ,Megha jain

The use of herbs as medicine has grown in popularity in this country over the past decade, contributing to a $4.1 billion supplement industry. The popularity of herbs is due to several factors: they can be purchased without a prescription, a belief that "natural" products are safer and the knowledge that many of our modern drugs are derived from herbs. Toxicity can occur when a herb with unknown toxicity is consumed, incorrect identification leads to substitution of an innocuous herb with a toxic one, preparations are contaminated with toxic non-herbal compounds or when a herb potentiates the nephrotoxic effect of a conventional therapy. Renal injury has been reported in association with several herbs. The best known herb induced chronic kidney disease (CKD) is aristolochic acid nephropathy.