Biochimie et physiologie : accès libre

Abstrait

Urinary Biochemistry is Used in the Diagnosis of Acute Kidney Injury

Jennifer Toledo*

Acute kidney damage is a clinical illness that complicates and affects the course of a large number of hospitalized patients. Recent breakthroughs in clinical and basic research will aid in the characterization of this condition and the understanding of its pathophysiology. With this information, we will be able to perform more reliable epidemiologic studies in order to acquire a better understanding of the syndrome’s impact. AKI is a condition with no single and distinct pathogenesis. Despite evidence that questions the use of biochemical indicators in clinical practise, they continue to be used. A better marker would include more particular information about the type, severity, and location of the injury. In this overview, we’ll look at the factors that influence urea and salt fractional excretion. We believe that routinely examining the microscopy and biochemistry of urine can help determine whether or not AKI is reversible. Early injury biomarkers could help direct clinical therapy.