Journal de médecine vétérinaire et de santé

Abstrait

Update of Usefulness and Adverse Effects of Nanoparticles on Animals and Human Health

Mahmoud M Elalfy, Mona G El-hadidy and Mamdouh M Abouelmagd

Nanotechnology has a potential application and a great biological role in veterinary diagnosis and in animal reproductive biotechnologies beside great impact on diagnosis in animal diseases. There is also a great interest from toxicologist for research on safety of different nanoparticles that used in cure of diseases. Nanoparticles reported to have various adverse effects in different animal tissue and also in human health. Various nanoparticles have toxic effect on liver, lung, skin, eye, reproductive disturbance and blood cells. The key mechanism of toxicity of nanoparticle is due to increase its concentration in non-target tissue of therapy through genotoxicity, oxidative stress or hemotoxic effects. On other word, nanoparticles could have adverse effects on healthy rather than diseased tissue.