Journal de la grossesse et de la santé infantile

Abstrait

Strategies to Reduce Infantile Cerebral Palsy

Kazuo Maeda*

Aim: To prevent cerebral palsy by avoiding fetal brain damage. Methods: 1. Emergency early delivery timing is before the loss of FHR variability, which is such severe fetal brain damage as anencephaly, 2. FGR caused by the fibrin deposit in placental intervillous space should be soluted to prevent severe hypoxia. 3. Preterm brain periventricular echo density (PVE) should be rejected to prevent PVL and CP, 4. Neonatal hypoxic ischemic encephalopathy (HIE) should be prevented by emergency C-section in sudden continuous bradycardia, and Developed HIE is treated by hypothermia. Anti-glutamate drug should be established. 5. Neonatal respiratory distress syndrome (RDS) is predicted by GLHW ultrasonic tissue characterization to treat by steroid in the fetus and artificial surfactant in neonate 6. Preeclampsia is treated by anti-sympathicotonic therapy to prevent placental infarction, hypoxia and CP, 7. Developed CP is treated by suitable stem cell therapy. Results: Effect to reduce infantile CP is shown in some strategies, while most of them should be established in the future.