Journal de biochimie et de biologie cellulaire

Abstrait

RNA's Multifaceted Roles: From Messengers to Masters of Regulation

Andresa Giombelli

RNA biology has emerged as a dynamic and intricate field that transcends its conventional role as a mere intermediary in genetic information flow. This article explores the diverse roles of ribonucleic acid (RNA) molecules in cellular processes, ranging from messenger RNA (mRNA) translation to the intricate regulatory mechanisms orchestrated by non-coding RNAs (ncRNAs). The significance of RNA modifications, epitranscriptomics, in modulating RNA function is highlighted. The potential of RNA-based therapeutics and technologies, such as mRNA vaccines and CRISPR-Cas-mediated RNA editing, is also discussed. As we delve deeper into the complexities of RNA biology, its impact on gene expression, disease mechanisms, and therapeutic advancements becomes increasingly evident.