Journal international de l'inflammation, du cancer et de la thérapie intégrative

Abstrait

Radiotherapy for Large Single Brain Metastasis of Non Small Cell Lung

Choi JH

Brain metastases are more common than all other primary intracranial tumors [1-3]. Lung cancer is the most common primary site [4-6]. Approximately 20– 50% of patients present with a single lesion in the brain. Patients with a single brain metastasis from non-small cell lung cancer (NSCLC) have the potential for long term survival [7,8]. Treatment for this lesion includes some combination of steroids, whole-brain radiation therapy (WBRT), local radiation therapy including stereotactic radiosurgery (SRS), and surgical resection. The management for these patients is controversial. Although radiation therapy is non-invasive, whole brain radiation therapy have some brain toxicities. This shifted away from whole brain radiation therapy (WBRT) toward local treatment modalities including radiosurgery (RS) and fractionated stereotactic radiation therapy (FSRT) [9-11].