Notre groupe organise plus de 3 000 séries de conférences Événements chaque année aux États-Unis, en Europe et en Europe. Asie avec le soutien de 1 000 autres Sociétés scientifiques et publie plus de 700 Open Access Revues qui contiennent plus de 50 000 personnalités éminentes, des scientifiques réputés en tant que membres du comité de rédaction.

Les revues en libre accès gagnent plus de lecteurs et de citations
700 revues et 15 000 000 de lecteurs Chaque revue attire plus de 25 000 lecteurs

Indexé dans
  • Index Copernic
  • Google Scholar
  • Ouvrir la porte J
  • JournalSeek de génamique
  • Infrastructure nationale du savoir de Chine (CNKI)
  • Bibliothèque de revues électroniques
  • Recherche de référence
  • Université Hamdard
  • EBSCO AZ
  • OCLC-WorldCat
  • Bibliothèque virtuelle de biologie (vifabio)
  • Publons
  • Fondation genevoise pour l'enseignement et la recherche médicale
  • Euro Pub
  • ICMJE
Partager cette page

Abstrait

Pleurodesis through Pleural Catheterization in Patients with Symptomatic Malignant Pleural Effusions: Which One is better? Talc, Bleomycin or Tetracycline?

Türkmen Çiftçi, Sercan Aksoy, Çağdaş Topel*, Devrim Akıncı, Ilkay S. Idilman, Umut Arslan, Erhan Akpınar, Bülent Erbil, Mehmet Mahir Kunt, Mehmet Ali Karaca, Okan Akhan

Purpose: To analyze the results of pleurodesis through pleural catheterization using talc slurry, bleomycin, and tetracycline in patients with symptomatic malignant pleural effusion (MPE) and to compare the efficacy, reliability and outcomes of these agents.
Methods: Talc (4 g), bleomycin (60.000 U) or tetracycline (1 g) was used for chemical pleurodesis in 271 patients. Successful pleurodesis was defined as no fluid build up and lack of recurrence of symptoms within the first 30 days after treatment. Data were analyzed using SPSS 15.0 for Windows.
Results: Pleural catheterization was performed in a total of 368 patients. Eighteen patients were lost to follow-up. Seventy-nine patients were excluded due to either of the following factors; trapped lung syndrome or patient lost during the early post-catheterization period due to advanced disease. In 271 patients chemical pleurodesis was performed with talc slurry (17.3%), bleomycin (13.7%) or tetracycline (49.1%). In 19.9% of the patients, multiple chemical agents were used in different sessions as successful results were not obtained with one agent. Clinical and radiological success was achieved in 78.2% of patients. There was no significant difference among 4 groups (talc slurry, bleomycin, tetracycline and multiple agents) in terms of clinical success, complication rates and median symptom-free life periods.
Conclusion: Talc slurry, bleomycin, or tetracycline administration through percutaneous pleural catheterization have comparable efficacy rates and safety profiles. If pleurodesis failure with one agent occurs, the attempt with other agents may result in success.

Avertissement: Ce résumé a été traduit à l'aide d'outils d'intelligence artificielle et n'a pas encore été examiné ni vérifié.