Biochimie et physiologie : accès libre

Abstrait

P- Bodies Composition, Properties, and Functions

Divya Singh

Processing bodies( P- bodies) are cytoplasmic ribonucleoprotein( RNP) granules primarily composed of translationally repressed mRNAs and proteins related to mRNA decay, suggesting places inpost-transcriptional regulation. P- bodies are conserved in eukaryotic cells and parade parcels of liquid driblets. still, the function of Pbodies in translational suppression and/ or mRNA decay remains contentious. Then we review recent advances in our understanding of the molecular composition of P- bodies, the interactions and processes that regulate P- body liquid – liquid phase separation( LLPS), and the cellular localization of mRNA decay ministry, in the environment of how these discoveries upgrade models of P- body function.