Journal international de l'inflammation, du cancer et de la thérapie intégrative

Abstrait

Lanthanum, Yttrium Iron Oxide with Nanoparticles Structural, Magnetic Analysis, and Their Anti-Cancer Application

Umadevi P, Baskaran I, Sathyaseelan B, Senthilnathan K, Manikandan E

The synthesis, characterization, and biological properties of Iron Oxide with Lanthanum and Yttrium oxide nanoparticles were discussed. The samples were prepared using the microwave-accelerated technique. The products were characterized using X-ray diffraction (XRD) and Vibrating Sample Magnetometer (VSM), and also subjected to MDA – MB – 231 breast cancer and Anti-cancer activity. XRD confirmed the crystalline nature and structural changes were also noticed as a function of the size of the rare-earth ion added.The formed NPs crystalline structure and its size (18 to 23) nm have been determined using XRD analysis. The saturation magnetization, coactivity and remanence indicate the super paramagnetic behavior, but the lanthanum and yttrium have weak magnetic properties when composited of the investigated samples.The samples were safe against MDA-MB-231 breast cancer cell lines. Besides, the microbial studies, the response in human breast cancer cells exposed to Lanthanum, Yttrium oxide with iron oxide NPswere analyzed with MDA MB 231 by MTT assay.