Tendances actuelles en oncologie gynécologique

Abstrait

Estimate the impact of cervical cancer on ovarian response and oocyte quality after controlled ovarian Hyperstimulation

Dimcho Bachvarov

Background : The purpose of this study was to estimate the impact of cervical cancer on ovarian response and oocyte quality after controlled ovarian hyperstimulation( COH). styles This retrospective case- control study estimated the impact of bone cancer on ovarian response and oocyte quality. Cancer cases with bone cancer witnessing controlled ovarian stimulation cycles to save fertility and age- and date- matched controls witnessing COH for in vitro fertilization( IVF) for manly or tubal gravidity were included in the study. Two hundred ninety- four women were enrolled 105 with bone cancer and 189 healthy women in the control group. The two groups were analogous in age, BMI and AMH values. Peak estradiol attention on day of induction, duration of stimulation, total quantum of gonadotropins administered, number of oocytes recaptured, rate of metaphase oocyte product, and number of immature oocytes and scars were anatomized.

Results: Taking into account factors that impact oocyte quality, similar as age, BMI, AMH, stimulation time, E2 position on the day of activation, total accretive FSH cure, stage, genotype, BRCA and hormone receptor status, univariate and multivariate analyzes were determined. bone cancer is a threat factor for the presence of deformed oocytes.

Conclusions: The opinion of bone cancer doesn't appear to be related to changes in ovarian reserve but to a decline in egg quality.