Biochimie et physiologie : accès libre

Abstrait

Clinical Tests Based on Disease Prevalence Related to Positive and Negative Application to Covid-19 Testing

Gongwen Wang

Molecular and serological tests play a crucial role within the diagnosis, monitoring and epidemiological investigation of the many diseases. They are often be positive or negative results. a completely unique coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused an ongoing pandemic that causes severe coronavirus disease 2019 (COVID-19) [1]. Infection by SARS-CoV-2 could also be identified by detecting viral RNA with macromolecule amplification tests (NAATs) or by viral antigens, or on reflection by documenting the presence of an immune reaction against the virus, as reflected by the presence of specific anti-SARS-CoV-2 antibodies [2]. The clinical performance is “ability of a biomarker to evolve to predefined clinical specifications in detecting patients with a specific clinical condition or during a physiological state”.