Biochimie et physiologie : accès libre

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Chromium and Zinc Level of Patients with Type 2 Diabetes and Non-Diabetes

Unjiati, Bambang Wirjatmadi and Merryana Adriani

Type 2 diabetes mellitus and its complications have become a serious public health problem and an important cause of morbidity, mortality and disability in worldwide. Type 2 diabetes caused by insulin resistance together with insulin deficiency, occurs in adulthood. Micro mineral that contribute to the occurrence of diabetes mellitus are chromium and zinc. This study aimed to determine differences level of chromium and zinc between patients with type 2 diabetes and non-diabetic in Hajj General Hospital, Surabaya.

This research is an observational study with cross sectional approach. The study was conducted in internal disease poly of Hajj General Hospital, Surabaya on June to July 2014 using simple random sampling as sampling method. Sample sizes are 30 people, consisting of 15 patients with type 2 diabetes and 15 non-diabetic patients. Blood tests performed in the laboratory and interview was conducted using a questionnaire. Bivariate analysis using Independent Sample T-test.

The results showed no significant difference of chromium (p<0.201) and zinc level (p<0.431) between type 2 diabetes group with non-diabetic. Average level of chromium and zinc in type 2 diabetic patients is lower than the non-diabetic.