Cancer du sein : recherche actuelle

Abstrait

Choroidal Metastasis as a First Sign of Recurrence in a Patient with Breast Cancer: A Case Report

Youssef Seddik*, Sami Aziz Brahmi, Ouissam Al-Jarroudi, Rania Chacha, Anne Dietemann Barabino, Stephane Ruck and Said Afqir

Choroidal metastasis is the most frequent ocular tumor. Due to its high vascularity, the choroid is particularly susceptible to hematogenous dissemination of cancer cells. The most common primary tumors in choroidal metastasis are located in the lung for men and the breast for women. We report a patient followed for breast cancer treated in June 2005. She was asymptomatic until February 2016, when she presented a progressive decrease in left eye’s visual acuity and headache. Funduscopic examination showed a left exudative retinal detachment. The brain Magnetic resonance imaging revealed a left choroid metastasis. The total body computer tomography scan showed a many lung, liver, peritoneal and bone metastases. The symptoms were improved after whole-brain radiotherapy and first line systemic chemotherapy based on Bevacizumab and weekly Paclitaxel.