Système gastro-intestinal et digestif

Abstrait

An Open Comparative Randomized Clinical Study of Plant Based Drugs Embelia Robusta Roxb and Mallotus Philippinensis Muell on Intestinal Parasites

Shishira Bharadwaj, Shraddha Nayak and Joshi VK

Background: Intestinal parasites are common cause of morbidity.

Aim: To compare the efficacy and safety of two plant based drugs Embelia robusta Roxb and Mallotus philippinensis Muell on intestinal parasites.

Methods: Forty Patients exhibiting symptoms of parasitic infection were diagnosed and confirmed by stool test. They were then randomized to either Embelia in a dose of 5 g or Mallotus in dose of 1 g with honey and jaggery as adjuvant respectively. Drugs were administered for a period of one week and follow-up was carried in 15 days and thereafter a month to observe symptomatic relief and presence or absence of ova/cyst in stool sample examination.

Results: Symptomatic relief was found in Mallotus while some symptoms still persisted with Embelia. Embelia robusta had 40% cure rate while Mallotus had 70% cure rate, but both the drugs did not result in any adverse effects.

Conclusions: It was observed that Mallotus philippinensis had better efficacy.