Journal de médecine et de chirurgie pédiatriques

Abstrait

An Extensive Single Centre experience with the Biological Prosthesis PermacolTM in Paediatric Surgery

Claudia Filisetti

Introduction: The use of prosthetic patches of non-absorbable materials represents a valid tool within the treatment of paries and diaphragmatic defects in paediatric age. In recent years analysis has developed biological dermal scaffolds made of a sheet of single-celled matrix that may give the required support and cut back the prevalence of complications from non-absorbable implant. We tend to gift our expertise and a scientific review to judge the employment of life restorative for paries closure in paediatric patients.

Methods: The study from January twenty09 to January 2015 concerned 20 patients treated with Permacol™ implant. we tend to discovered operative complications solely in patients treated for paries closure, that is that the major indication for the employment of Permacol™. We tend to conducted a scientific review and meta-analysis (according to PRISMA) on PubMed/Medline, Scopus and EMBASE relating to the employment of biological restorative in paediatric population considering the incidence of complications because the primary outcome.

Results: 3/20 patients seasoned complications: a pair of patients with skin gangrene cured guardedly and one of them developed hernia so just one patient with incisional herniation had vital surgery complication. In patients World Health Organization were for good deep-seated with Permacol™ it's not determined adverse reactions with optimum purposeful outcome.

Conclusion: In accordance with the few information (case reports and case series) according in literature concerning paediatric patients, our expertise in several pathologies and applications has shown the effectiveness of Permacol™, especially for the non-occurrence of infections that usually have an effect on the employment of restorative [1].