Système gastro-intestinal et digestif

Abstrait

Acute Hepatitis C Virus Infection and Directly Acting Anti-Hepatitis C Virus Drugs

Alhaddad OM, Elsabaawy MM, Elshaarawy O, Elsabaawy DM, Mansour T

The best of care of Acute hepatitis C (AHC) infections in the evolving era of all oral directly acting antiviral drugs (DDAs) needs revision. The inevitable chronic liver disease in 80% of AHC infections justifies the advent of DDAs that expectedly will guarantee high cure rates. Unlike interferons, the short and ultra-short all oral DDAs regimens had revolutionized treatment strategies with better adherence and fewer complications. However, the costly price of DAAs added to the average expertise is still contrarily active. Up-to-date, studies concerning DAAs treatment for AHC mono-infection are sparse; indeed this represents an unmet need in modern AHC management.