Journal de neuroimmunologie clinique et expérimentale

Abstrait

A Study to Assess Various Factors Contributing to the Development of Thymic Hyperplasia, Higher MGFA Classification, and Duration of Disorder Prior to Prednisone Treatment

Fnu Shwetank

Patients in the pubertal onset team (n=148) had a worse disorder path than those in the prepubertal crew (n=711), which include a greater incidence of generalized MG (GMG) at presentation, generalization of ocular MG (OMG), and greater severe Myasthenia Gravis Foundation of America (MGFA) classification. All sufferers have been at the beginning dealt with pyridostigmine, 657 with prednisone, and 196 with immunosuppressant’s. However, 226 sufferers have been resistant to prednisone treatment. Multivariate evaluation published that thymic hyperplasia, greater MGFA class, disorder length earlier than prednisone administration, and thymectomy earlier than prednisone administration had been unbiased predictors of prednisone resistance.