Système gastro-intestinal et digestif

Abstrait

A Clinical Study on the Relationship Between Lymph Nodes Metastasis in Early Gastric Carcinoma and Clinicopathological Factors and Reasonable Treatment Options

Xin Zhang, Rui Zheng, Guo Wei, Jian-wei Bi

Objective: To investigate the rule of lymph node metastasis in early gastric cancer , in order to provide a reference for the reasonable treatment options.

Method: To retrospectively analyze the clinical data of 271 cases of EGC patients from October 2005 to October 2011.

Results: Both univariate analysis and multivariate analysis results show that tumor size, pathological classification and depth of invasion are correlated with lymph node metastasis. The further analysis of the rate of lymph node metastasis shows that lymph node metastasis cannot be found in the patients with differentiated tumor of which the size is below 3.0cm when tumor invades mucosal layer; at the same time, lymph node metastasis cannot be found in the patients with undifferentiated tumor whose size is below 2.0cm as well. However, lymph node metastasis occurs in all the sorts when tumor invades submucosal layer.

Conclusion: Tumor size, invasive depth, pathological classification, and lymphatic tube invasion were closely related to lymph node metastasis in patients with early gastric cancer, patients with early gastric cancer are recommended to have a preoperative Endoscopic Ultrasonographic (EUS) scan as well as pathological screenings for deciding the most appropriate type of surgery.